The main mission of Computational and Chemical Biology is to develop innovative computational tools and algorithms to enhance the discovery of novel and better medicines. A further strategic asset of our research line is to design, synthesize, and biologically evaluate novel lead candidates for cancer, neurodegenerative diseases, and neglected tropical diseases. The team is composed of a core of computational scientists, who work in strict collaboration with chemists and biologists towards interdisciplinary goals in drug discovery.
Computational and Chemical Biology
Projects
Progetto 5000genomi@VdA, supported by Programma Investimenti per la crescita e l’occupazione 2014/20 (FESR) and Programma Investimenti in favore della crescita e dell’occupazione 2014/20 (FSE) Per maggiori dettagli si veda il sito del Progetto www.5000genomivda.it
The latest publications
2024
Gözde F., Landuzzi F., Brambilla A., Charrance D., Furia F., Trova S., Peracino A., Camenisch G., Waldvogel D., Howard-McCombe J., et al.
A highly contiguous reference genome for the Alpine ibex (Capra ibex)
bioRxiv
2024
Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti M., Cavalli A.
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery
National Congress of the Italian Chemistry Society 2024
2024
Abate C., Decherchi S., Cavalli A.
AMCG: a graph dual atomic-molecular conditional molecular generator
Machine Learning: Science and Technology, vol. 5, (no. 3)
People
Principal Investigator
Computational and Chemical Biology
IIT OpenTalk Magazine - Lab Highlights Show all >